Dexamethasone for acute migraine

In this meta-analysis of 7 RCT in 742 patients, the addition of a one-time dose of dexamethasone (IV dose range 4-10mg) to standard migraine treatment reduced the rate of moderate to severe headache at 24-72 hour follow up (ARR 10%) (abstract). This analysis gives the best evidence to date for adding a low cost, low risk, adjuvant therapy for acute migraine attacks.

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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