Dopamine or Norepinephrine for shock?

By  |  March 6, 2010 | 

In this trial of 1679 patients in shock, they were randomized to norepinephrine or dopamine as first line therapy (with open-label second-line pressors as needed). There was no difference in the primary outcome between the groups (28 day mortality), but the dopamine group had higher rates of arrythmias, and higher rates of 28 day mortality in the cardiogenic shock subgroup. Norepinephrine should be considered for first line therapy for shock patients, especially those with cardiogenic shock (abstract)

About the Author:

Danielle Scheurer
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.


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