In non-ICU patients admitted with CAP, the ATS/ISDA (guidelines) recommend fluoroquinolone monotherapy or combination of cephalosporin / macrolide. In this large retrospective cohort, treatment with either of these was associated with significantly lower mortality (in-hospital, 14 day, and 30 day) (compared to cephalosporin monotherapy). There is no evidence to veer from these simple straightforward guidelines in patients with CAP (citation: Bratzler DW, CID 2008;47:S193)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.