In this small cohort of 56 patients with left sided endocarditis, of the 40 that underwent brain MRI, 80% had evidence of brain emoblization (48% were subclinical, 33% were clinical stroke). Of those with staph aureus, 95% had evidence of brain embolization. Mortality at 30 days was much higher for those with stroke (46%) and subclinical brain emoblization (32%) than those without brain embolization (0%). Subclinical brain embolization is very common in patients with endocarditis, and is associated with a poor prognosis (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.