In this industry sponsored randomized trial of 1952 healthy adults (aged 18 to 49), the inactivated (intramuscular) vaccine outperformed the live-attenuated (nasal spray). Overall 6% of participants had lab-confirmed influenza, and there was a 50% reduction in influenza cases in the inactivated vaccine group compared to the live-attenuated group. Inactivated seasonal influenza vaccination reduces lab-confirmed influenza more than live-attenuated in healthy adults (abstract).
by Deepak Asudani, MD, MPH, FHM Whether it is the prompt and expeditious international collaboration to develop an Ebola vaccine, or tardy but promising development of the first anti parasitic malarial vaccine or the fascinating technology utilizing synthetic DNA for vaccine development against MERS, these developments promise to highlight significant strides in vaccine development for […]
Economists describe preferences in two ways: revealed and stated. Say, for example, I asked you to implement a penalty program for your team with the goal of decreasing the number of occasions members did not clean their hands after a patient encounter. Because you know bad hands equal bad outcomes, you’re apt to offer up […]
by Eric Howell, MD, SFHM “Tell me what you know about antibiotics.” That’s the discussion I start with hospitalized patients all the time, right after they ask me to prescribe antibiotics for their simple cough, or other viral-like illness. And, from their perspective, asking for antibiotics makes sense. After all, antibiotics have been the physician’s […]