In this retrospective cohort, researchers found that proteinuria and low GFR both independently increased the risk of thromboembolic disease in patients with afib. Proteinuria was associated with a RR=1.5, GFR between 45-60 with a RR=1.2, and GFR <45 with a RR=1.4. Since these are not incorporated into most risk predictors of stoke with afib, we should also consider these risk factors when deciding the risk-benefit ratio of anticoagulation in patients with afib (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.