In 2 recent studies published in NEJM, both essentially show that DES and bare metal stents have similar safety profiles, but that DES have lower restenosis rates. The first study looked at outcomes of almost 30,000 patients in a large Swedish registry that had a single stent, and found no difference in death or MI, but much lower clinical restenosis in the DES patients (abstract). The other RCT of over 3000 STEMI patients found no difference in death or thrombosis between the stent types, but the DES group required fewer revasularizations (abstract). Both of these trials support the use of DES in those able and willing to continue long-term dual anti-platelet therapy.
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.