In this retrospective analysis of 5777 hospitalized patients, ESR and CRP “agreed” (both elevated or both normal) in 67% of patients. Of the 33% disagreements, chart review found the majority of disagreements were an elevated ESR and normal CRP, where the CRP more accurately reflected the patient’s condition (resolving inflammatory condition or false positive ESR). In suspected inflammatory conditions, CRP is a more accurate measure in hospitalized patients, with fewer false negatives or positives than ESR (abstract)
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