In this retrospective analysis of 5777 hospitalized patients, ESR and CRP “agreed” (both elevated or both normal) in 67% of patients. Of the 33% disagreements, chart review found the majority of disagreements were an elevated ESR and normal CRP, where the CRP more accurately reflected the patient’s condition (resolving inflammatory condition or false positive ESR). In suspected inflammatory conditions, CRP is a more accurate measure in hospitalized patients, with fewer false negatives or positives than ESR (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.