Non-invasive ventilation after extubation

In this trial of 106 intubated patients (with hypercarbic respiratory failure), they were randomized after extubation to 24 hours of non-invasive positive pressure ventilation (NIPPV) or oxygen. Those in the NIPPV group had significantly less respiratory failure at 72 hours (15% vs 48%) and lower mortality at 90 days (11% vs 31%). NIPPV should be considered for all patients post-extubation from hypercarbic respiratory failure (abstract).

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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