Predicting Cdiff recurrence

In this validation cohort of 89 patients with Cdiff, 3 clinical factorswere used to predict recurrence, including age >65, need for antibiotics after Cdiff treatment, or severe/fulminant illness (based on the 4 point Horn Index, which is a clinical judgement of severity of illness; mild, moderate, severe or fulminant). Those with 0-1 risk factors had recurrence risk of 13%, and those with 2-4 risk factors had recurrence risk of 37% (with an AUC of 0.80, CI 0.67-0.92). This simple clinical prediction rule can help facilitate prompt recognition, diagnosis, and treatment of patients at risk for recurrent (abstract).

Danielle Scheurer

Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

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