In this validation cohort of 89 patients with Cdiff, 3 clinical factorswere used to predict recurrence, including age >65, need for antibiotics after Cdiff treatment, or severe/fulminant illness (based on the 4 point Horn Index, which is a clinical judgement of severity of illness; mild, moderate, severe or fulminant). Those with 0-1 risk factors had recurrence risk of 13%, and those with 2-4 risk factors had recurrence risk of 37% (with an AUC of 0.80, CI 0.67-0.92). This simple clinical prediction rule can help facilitate prompt recognition, diagnosis, and treatment of patients at risk for recurrent (abstract).
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