In this validation cohort of 89 patients with Cdiff, 3 clinical factorswere used to predict recurrence, including age >65, need for antibiotics after Cdiff treatment, or severe/fulminant illness (based on the 4 point Horn Index, which is a clinical judgement of severity of illness; mild, moderate, severe or fulminant). Those with 0-1 risk factors had recurrence risk of 13%, and those with 2-4 risk factors had recurrence risk of 37% (with an AUC of 0.80, CI 0.67-0.92). This simple clinical prediction rule can help facilitate prompt recognition, diagnosis, and treatment of patients at risk for recurrent (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]