In patients with asymptomatic aortic stenosis (AS), predicting the risk of death or need for valve replacement would be useful. In this prospective cohort of 107 patients with moderate to severe AS (peak aortic-jet velocity>3 m/sec or valve area <1.5), the risk of death or valve replacement occurred in 58%. Factors independently associated with the outcome were female sex, BNP, and peak aortic jet velocity. Event free survival was 80% in the lowest risk quartile, and only 7% in the highest risk quartile. These 3 factors can be used to estimate risk of death or need for valve replacement in patients with asymptomatic AS (abstract).
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.