In this single center cohort of 267 patients with acute variceal bleeding, researchers derived and validated a simple risk model to determine the 6-week risk of death. They found 3 parameters (Child-Pugh score, bacterial infection, and creatinine level) predicted 6 week death more accurately than either the Child-Pugh score alone, or the MELD score. Those at the lowest and highest risk groups had mortality rates of 8% and 73% respectively. This easy to calculate risk score can be valuable in predicting short-term risk in variceal bleeding (abstract).
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]