In this large cohort of patients with acute kidney injury, proteinuria predicted the risk of injury as well as did GFR. Risk increased with increasing levels of proteinuria, and the highest risk were patients with both proteinuria and low GFR. Currently GFR is used to predict risk of acute kidney injury (and therefore to avoid nephrotoxins such as NSAIDs or IV contrast), but this suggests that proteinuria may need to be evaluated as well (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.