This large cohort of patients on warfarin who experienced a GI bleed found 59% resumed warfarin within 90 days. Those that resumed were significantly less likely to experience thrombosis (hazard ratio 0.05, CI 0.01-0.58) or death (hazard ratio 0.31, CI 0.15-0.62), and did not have a higher risk of bleeding, compared to those that did not resume warfarin within 90 days. This study suggests that early re-initiation of warfarin after a GI bleed results in better clinical outcomes that waiting for 90 days or later (abstract)
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.