Downside of oral/digestive decontamination

By  |  April 1, 2010 | 

In a randomized controlled trial published in 2009 (abstract), intubated ICU patients who underwent oral/digestive decontamination had lower mortality than control patients. However, a follow-up study from this trial shows that the the point prevalence of resistant gram-negative colonization rates were higher after the intervention than before the intervention. This may give pause to those ICU’s considering routine decontamination protocols, and further long-term follow-up of clinical outcomes from this study will be interesting (abstract).

Leave A Comment

About the Author:

Danielle Scheurer
Dr. Scheurer is a clinical hospitalist and the Medical Director of Quality and Safety at the Medical University of South Carolina in Charleston, South Carolina, and is Assistant Professor of Medicine. She is a graduate of the University of Tennessee College of Medicine, completed her residency at Duke University, and completed her Masters in Clinical Research at the Medical University of South Carolina. She also serves as the Web Editor and Physician Advisor for the Society of Hospital Medicine.

Categories

Related Posts

By  | October 8, 2015 |  0
by Deepak Asudani, MD, MPH, FHM Whether it is the prompt and expeditious international collaboration to develop an Ebola vaccine, or tardy but promising development of the first anti parasitic malarial vaccine or the fascinating technology utilizing synthetic DNA for vaccine development against MERS, these developments promise to highlight significant strides in vaccine development for […]
By  | August 24, 2015 |  5
  Economists describe preferences in two ways: revealed and stated.  Say, for example, I asked you to implement a penalty program for your team with the goal of decreasing the number of occasions members did not clean their hands after a patient encounter.  Because you know bad hands equal bad outcomes, you’re apt to offer up […]
By  | June 2, 2015 |  1
by Eric Howell, MD, SFHM “Tell me what you know about antibiotics.” That’s the discussion I start with hospitalized patients all the time, right after they ask me to prescribe antibiotics for their simple cough, or other viral-like illness. And, from their perspective, asking for antibiotics makes sense. After all, antibiotics have been the physician’s […]