In this small trial of patients presenting with hemodynamically significant hematochezia and negative upper endoscopy, they were randomized to urgent colonoscopy (with 12 hours) or elective colonoscopy (within 60 hours). There were no significant differences between the groups in further bleeding, transfusion need, length of stay, or hospital cost. For now, there is no evidence that colonoscopy needs to be urgently performed in patients with hematochezia and negative upper endoscopy (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]