In this large, multi-national point prevalence survey of 13,796 ICU patients (EPIC-II), 51% were considered infected, and 71% were receiving antibiotics. Of those with positive isolates, 62% were gram negative, 47% were gram positive, and 19% were fungi. ICU mortality was 25% and 11% for infected and non-infected patients, respectively. Hospital mortality was 33% and 15% respectively. Infections in ICU patients are frequent and associated with high mortality (abstract).
by Deepak Asudani, MD, MPH, FHM Whether it is the prompt and expeditious international collaboration to develop an Ebola vaccine, or tardy but promising development of the first anti parasitic malarial vaccine or the fascinating technology utilizing synthetic DNA for vaccine development against MERS, these developments promise to highlight significant strides in vaccine development for […]
Economists describe preferences in two ways: revealed and stated. Say, for example, I asked you to implement a penalty program for your team with the goal of decreasing the number of occasions members did not clean their hands after a patient encounter. Because you know bad hands equal bad outcomes, you’re apt to offer up […]
by Eric Howell, MD, SFHM “Tell me what you know about antibiotics.” That’s the discussion I start with hospitalized patients all the time, right after they ask me to prescribe antibiotics for their simple cough, or other viral-like illness. And, from their perspective, asking for antibiotics makes sense. After all, antibiotics have been the physician’s […]