This large retrospective database analysis found recurrent Cdiff was significantly more common in those exposed to a PPI than those not exposed (25% vs 19%) (adjusted hazard ratio 1.42). Risks and benefits of PPI therapy in patients with Cdiff need to be carefully weighed, to reduce the risk of recurrence (abstract)
This large systematic review found rectal NSAIDs significantly reduced the risk of post-ERCP pancreatitis compared to pancreatic duct stents (abstract).
This large population-based cohort found the most common causes of drug induced liver injury to be augmentin and diclofenac, followed by herbal and nutritional supplements (abstract).
This large trial of patients with a relative contraindication for enteral feeds were randomized to early TPN or usual care. There were no differences in the groups in 60 day mortality or LOS, but those on TPN did have a shorter time ventilated and less muscle/fat loss. It is unclear based on this trial if […]