In this large derivation and validation cohort, 5 clinical risk factors were found to significantly increase the risk of death in those presenting with acute UGI bleed: these included age >65, altered mental status, systolic BP<90, INR >1.5, or albumin <3. The risk of death increased with the number of factors present, from <1% to 25% with zero to 5 factors, respectively. This can be used to predict need for urgent endoscopy and/or ICU disposition (abstract)
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