In this single-center randomized trial, serum procalcitonin was measured for all ICU patients with suspected infections, but half of the patients’ procalcitonin values were blinded. There were no differences between the groups in antibiotic treatment days. Also, 34% of those without confirmed infection had high procalcitonin levels, and 15% of those with confirmed infection had low procalcitonin levels (abstract). In this study of ICU patients with suspected infections, procalcitonin levels did not effectively rule in or rule out confirmed infections, and did not reduce antibiotic days.
by Deepak Asudani, MD, MPH, FHM Whether it is the prompt and expeditious international collaboration to develop an Ebola vaccine, or tardy but promising development of the first anti parasitic malarial vaccine or the fascinating technology utilizing synthetic DNA for vaccine development against MERS, these developments promise to highlight significant strides in vaccine development for […]
Economists describe preferences in two ways: revealed and stated. Say, for example, I asked you to implement a penalty program for your team with the goal of decreasing the number of occasions members did not clean their hands after a patient encounter. Because you know bad hands equal bad outcomes, you’re apt to offer up […]
by Eric Howell, MD, SFHM “Tell me what you know about antibiotics.” That’s the discussion I start with hospitalized patients all the time, right after they ask me to prescribe antibiotics for their simple cough, or other viral-like illness. And, from their perspective, asking for antibiotics makes sense. After all, antibiotics have been the physician’s […]